The broad-line region and dust torus size of the Seyfert 1 galaxy PGC50427

We present the results of a three years monitoring campaigns of the $z = 0.024$ type-1 active galactic nucleus (AGN) PGC50427. Through the use of Photometric Reverberation Mapping with broad and narrow band filters, we determine the size of the broad-line emitting region by measuring the time delay between the variability of the continuum and the H$\alpha$ emission line. The H$\alpha$ emission line responds to blue continuum variations with an average rest frame lag of $19.0 \pm 1.23$ days. Using single epoch spectroscopy we determined a broad-line H$\alpha$ velocity width of 1020 km s$^{-1}$ and in combination with the rest frame lag and adoption a geometric scaling factor $f = 5.5$, we calculate a black hole mass of $M_{BH} \sim 17 \times 10^{6} M_{\odot}$. Using the flux variation gradient method, we separate the host galaxy contribution from that of the AGN to calculate the rest frame 5100\AA~ luminosity at the time of our monitoring campaign. The rest frame lag and the host-subtracted luminosity permit us to derive the position of PGC50427 in the BLR size -- AGN luminosity diagram, which is remarkably close to the theoretically expected relation of $R \propto L^{0.5}$. The simultaneous optical and NIR ($J$ and $K_{s}$) observations allow us to determine the size of the dust torus through the use of dust reverberation mapping method. We find that the hot dust emission ($\sim 1800K$) lags the optical variations with an average rest frame lag of $46.2 \pm 2.60$ days. The dust reverberation radius and the nuclear NIR luminosity permit us to derive the position of PGC50427 on the known $\tau - M{V}$ diagram. The simultaneus observations for the broad-line region and dust thermal emission demonstrate that the innermost dust torus is located outside the BLR in PGC50427, supporting the unified scheme for AGNs. (Abstract shortened, see the manuscript.)Comment: 11 pages, 23 figures, accepted for publication in Astronomy and Astrophysic

The Cyclophilin-Binding Agent Sanglifehrin A Is a Dendritic Cell Chemokine and Migration Inhibitor

Sanglifehrin A (SFA) is a cyclophilin-binding immunosuppressant but the immunobiology of action is poorly understood. We and others have reported that SFA inhibits IL-12 production and antigen uptake in dendritic cells (DC) and exhibits lower activity against lymphocytes. Here we show that SFA suppresses DC chemokine production and migration. Gene expression analysis and subsequent protein level confirmation revealed that SFA suppressed CCL5, CCL17, CCL19, CXCL9 and CXCL10 expression in human monocyte-derived DC (moDC). A systems biology analysis, Onto Express, confirmed that SFA interferes with chemokine-chemokine receptor gene expression with the highest impact. Direct comparison with the related agent cyclosporine A (CsA) and dexamethasone indicated that SFA uniquely suppresses moDC chemokine expression. Competitive experiments with a 100-fold molar excess of CsA and with N-Methyl-Val-4-cyclosporin, representing a nonimmunosuppressive derivative of CsA indicated chemokine suppression through a cyclophilin-A independent pathway. Functional assays confirmed reduced migration of CD4+ Tcells and moDCs to supernatant of SFA-exposed moDCs. Vice versa, SFA-exposed moDC exhibited reduced migration against CCL19. Moreover, SFA suppressed expression of the ectoenzyme CD38 that was reported to regulate DC migration and cytokine production. These results identify SFA as a DC chemokine and migration inhibitor and provide novel insight into the immunobiology of SFA

Observation of isotonic symmetry for enhanced quadrupole collectivity in neutron-rich 62,64,66Fe isotopes at N=40

The transition rates for the 2_{1}^{+} states in 62,64,66Fe were studied using the Recoil Distance Doppler-Shift technique applied to projectile Coulomb excitation reactions. The deduced E2 strengths illustrate the enhanced collectivity of the neutron-rich Fe isotopes up to N=40. The results are interpreted by the generalized concept of valence proton symmetry which describes the evolution of nuclear structure around N=40 as governed by the number of valence protons with respect to Z~30. The deformation suggested by the experimental data is reproduced by state-of-the-art shell calculations with a new effective interaction developed for the fpgd valence space.Comment: 4 pages, 2 figure

Lifetime measurements in 63^{63}Co and 65^{65}Co

Lifetimes of the $9/2^-_1$ and $3/2^-_1$ states in $^{63}$Co and the $9/2^-_1$ state in $^{65}$Co were measured using the recoil distance Doppler shift and the differential decay curve methods. The nuclei were populated by multi-nucleon transfer reactions in inverse kinematics. Gamma rays were measured with the EXOGAM Ge array and the recoiling fragments were fully identified using the large-acceptance VAMOS spectrometer. The E2 transition probabilities from the $3/2^-_1$ and $9/2^-_1$ states to the $7/2^-$ ground state could be extracted in $^{63}$Co as well as an upper limit for the $9/2^-_1\rightarrow7/2^-_1$ $B$(E2) value in $^{65}$Co. The experimental results were compared to large-scale shell-model calculations in the $pf$ and $pfg_{9/2}$ model spaces, allowing to draw conclusions on the single-particle or collective nature of the various states.Comment: 8 pages, 8 figures, 1 table, accepted for publication in Physical Review

Identifying Boosted Objects with N-subjettiness

We introduce a new jet shape -- N-subjettiness -- designed to identify boosted hadronically-decaying objects like electroweak bosons and top quarks. Combined with a jet invariant mass cut, N-subjettiness is an effective discriminating variable for tagging boosted objects and rejecting the background of QCD jets with large invariant mass. In efficiency studies of boosted W bosons and top quarks, we find tagging efficiencies of 30% are achievable with fake rates of 1%. We also consider the discovery potential for new heavy resonances that decay to pairs of boosted objects, and find significant improvements are possible using N-subjettiness. In this way, N-subjettiness combines the advantages of jet shapes with the discriminating power seen in previous jet substructure algorithms.Comment: 26 pages, 26 figures, 2 tables; v2: references added; v3: discussion of results extende

Jet Substructure Without Trees

We present an alternative approach to identifying and characterizing jet substructure. An angular correlation function is introduced that can be used to extract angular and mass scales within a jet without reference to a clustering algorithm. This procedure gives rise to a number of useful jet observables. As an application, we construct a top quark tagging algorithm that is competitive with existing methods.Comment: 22 pages, 16 figures, version accepted by JHE

Jet Dipolarity: Top Tagging with Color Flow

A new jet observable, dipolarity, is introduced that can distinguish whether a pair of subjets arises from a color singlet source. This observable is incorporated into the HEPTopTagger and is shown to improve discrimination between top jets and QCD jets for moderate to high pT.Comment: 8 pages, 6 figures (updated to JHEP version

Structure of Fat Jets at the Tevatron and Beyond

Boosted resonances is a highly probable and enthusiastic scenario in any process probing the electroweak scale. Such objects when decaying into jets can easily blend with the cornucopia of jets from hard relative light QCD states. We review jet observables and algorithms that can contribute to the identification of highly boosted heavy jets and the possible searches that can make use of such substructure information. We also review previous studies by CDF on boosted jets and its measurements on specific jet shapes.Comment: invited review for a special "Top and flavour physics in the LHC era" issue of The European Physical Journal C, we invite comments regarding contents of the review; v2 added references and institutional preprint number